Clemson is about 2.5 hours from Charlotte, N.C., 1 hour from Greenville, S.C., and 2.5 hours from Atlanta. See Google Maps for specific driving directions and detail maps.
Take Interstate-85 North toward Charlotte, N.C. Take exit 19B to U.S. 76/S.C. 28 West to Clemson. Turn left onto Perimeter Road, once in Clemson. Then take a left onto Cherry Road. Then take a slight right onto Old Stadium Road. Finally turn left onto Madren Center Drive.
Take I-85 South toward Atlanta. Take exit 19B to U.S. 76/S.C. 28 West to Clemson. Turn left onto Perimeter Road, once in Clemson. Then take a left onto Cherry Road. Then take a slight right onto Old Stadium Road. Finally turn left onto Madren Center Drive.
Take I-126 West to I-26 West toward Spartanburg, S.C. Exit onto I-385 West to Greenville, S.C. Exit onto I-85 South toward Atlanta. Then take exit 19B to U.S. 76/S.C. 28 West to Clemson. Turn left onto Perimeter Road, once in Clemson. Then take a left onto Cherry Road. Then take a slight right onto Old Stadium Road. Finally turn left onto Madren Center Drive.
Take I-95 North toward Fayetteville, N.C. Exit onto I-26 West toward Spartanburg, S.C. Exit onto I-385 West toward Greenville, S.C. Then exit onto I-85 South toward Atlanta. Then, take exit 19B to U.S. 76/S.C. 28 West to Clemson. Turn left onto Perimeter Road, once in Clemson. Then take a left onto Cherry Road. Then take a slight right onto Old Stadium Road. Finally turn left onto Madren Center Drive.
Take I-240 West to I-40 East/I-26 East, then continue onto I-26 East toward Hendersonville, N.C./Spartanburg, S.C. Next, exit onto U.S. 25 South toward Greenville. Then exit onto U.S. 123 West toward Easley. Follow U.S. 123 West into Clemson. Turn left onto U.S. 76 East. Turn right onto Perimeter Road. Turn left onto Cherry Road. Then slight right onto Old Stadium Road. Finally turn left onto Madren Center Drive.
The international airport at Greenville/Spartanburg is 45 minutes (45 miles) from Clemson. This airport is serviced by Allegiant Air, American Airlines, Delta, Southwest, United and US Airways. The airports in Atlanta and Charlotte are each about a two-hour drive from the University. Clemson is easily accessible off Interstate 85 (10-minute drive).